Ahvaz Jundishapur University of Medical Sciences, Iran
Posters & Accepted Abstracts: J Liver
Currently 3 major chronic liver diseases include hepatitis B, hepatitis C and non alcoholic fatty liver disease (NAFLD). Currently hepatitis B is potentially preventable by active and passive immunization and many countries have started general vaccination against HBV since 2 decade ago. On the other hand with introduction of direct acting agents (DAA) against hepatitis C, the SVR rate has raised to more than 90%. So theoretically this virus is eradicable, even our major challenge in this field is not virus per se but also patients’ behavior, personality and compliance. Based on these facts, it is imaginable that in the next decades, our major problem in the field of hepatology would be challenging with NAFLD and its potential complication, liver cirrhosis. In the last few decades, the prevalence of NAFLD has grown dramatically and while we relate this disorder mostly to sedentary life style, this type of life style actually has been adopted much earlier than fatty liver pandemic and precedes it for more than 30 years. So we should think about some reason else and keep in mind the celiac story. Currently the prevalence of celiac disease and gluten sensitivity problems is increasing year by year because the quality of nowadays wheat differs with what we ate 50 years ago mostly due to genetic manipulation to be more resist against jassids and achieving more harvest. May be the same story is happening about poultry, dairy and or protein industrial products and immunogenicity have has a role in fatty liver disorders.
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