Animal blood as a source for the development of fabricated nanobiocomposite and their potential biomedical applications
3rd International Conference on Nanotek & Expo
December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

M. Chamundeeswari and T. P Sastry

Accepted Abstracts: J Nanomed Nanotechnol

Abstract:

Multifunctional nanobiocomposite (NBC) can be fabricated by functionalizing suitable materials on to the nanomaterials. Though many types of nanoparticles are used in biomedical applications, in this study, we have focused on iron nanoparticles (INPs). A NBC was prepared by coating chitosan on to the INPs and coupling the folic acid (F) to the chitosan (C) molecules. Thus prepared NBC (INP-CF) was evaluated for its biocompatibility, toxicity and haemocompatibilty. Fourier transform infrared spectroscopy, X-ray diffraction techniques, Transmission electron microscopy, Scanning electron microscopy, Energy dispersive X-ray spectroscopy, Vibrational sample magnetometer have confirmed the formation of NBC. In vitro studies were carried out using breast cancer cell lines (MCF-7) and studied the efficacy of prepared NBC using magnetic resonance imaging techniques. The results have revealed the penetration of NBC into the cancer cells. These results indicate the possible use of the NBC as multifunctional agent for treatment of cancer

Biography :

M. Chamundeeswari is an Associate Professor in St. Joseph?s College of Engineering and has completed her B.Pharm. (Pharmacy) in April 1999 from Dr. M. G. R Medical University, Qualified GATE 2002, M.Tech., (Industrial Biotechnology) in May?2004 and Ph.D. (Nanobiotechnology) in Aug?2012, from Anna University, Chennai, India. She has participated in several workshops, seminars and conferences. She has published research papers in reputed International journals with good impact factor and was awarded ?Vical Award? for best paper presentation in conference held at Jalandhar, for Indian Institute of chemical engineers in 2009. One of her research article was highlighted in ?Nature India? (May?2011 in Research Highlights), subsidiary of ?Nature?.