Li Cheng1, Janet Wing1, Kai- chow Choi1, Sek- ying Chair1 and Xiao- mei Li2
1The Chinese University of Hong Kong, China 2Xi�??an Jiaotong University, China
Posters-Accepted Abstracts: J Diabetes Metab
Objective: This systematic review aimed to synthesize the best available evidence of self- management interventions to determine their efficacy in patients with poorly controlled Type 2 Diabetes. Methods: Major English and Chinese electronic databases were searched upto Dec 2014 for randomized controlled trials of selfmanagement interventions for patients with poor glycemic control (HbA1c> 7.5% (58 m mol/mol)). Two authors independently assessed the studies eligibility and extracted data by using a standard form. Results: Totally seventeen trials with 3211 participants with poorly controlled Type 2 Diabetes were included in the review. Metaanalysis showed that self-management interventions had beneficial effect on HbA1c in all short-term [mean difference (MD) �??0.42% (�??4.6 mmol/mol) (95% CI: �??0.63, �??0.20%)], intermediate-term [MD: �??0.44% (�??4.8 mmol/mol) (95% CI: �??0.74, �??0.14%)] and longterm [MD: �??0.45% (�??4.9mmol/mol) (95% CI: �??0.66, �??0.23%)]. Further subgroup analyses indicated the pooled effects were more desirable in studies delivered in weekly session, with duration of intervention less than 6 months and using behavioral approach. Conclusions: Type 2 Diabetes patients with poor glycemic control could benefit from self- management interventions. Practice Implications: The need for more effective interventions for these vulnerable patients remains urgent. There is also a clear need to establish knowledge about the mechanisms of the beneficial approaches and ingredients for patients with poor glycemic control.
Email: lilycheng@cuhk.edu.hk
