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Yung-Chih Kuo
National Chung Cheng University, Taiwan
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Neurology Congress 2017: Neuroprotection against apoptosis of SK-N-MC cells using RMP-7- and lactoferrin-grafted liposomes carrying quercetin - Yung-Chih Kuo - National Chung Cheng University
Author(s): Yung-Chih Kuo*
A drug delivery system of quercetin (QU)- exemplified liposomes (LS) united with RMP-7, a bradykinin simple, and lactoferrin (Lf) was produced for saturating the blood–mind hindrance (BBB) and saving declined neurons as an Alzheimer's malady (AD) pharmacotherapy. This colloquial plan of RMP-7-Lf-QU-LS was utilized to navigate human mind microvascular endothelial cells (HBMECs) controlled by human astrocytes (HAs) and to treat SK-N-MC cells after an affront with cytotoxic β-amyloid (Aβ) fibrils. We found that surface RMP-7 and Lf upgraded the penetrability for QU over the BBB without actuating solid poisonousness and harming.. View more»