Modern Chemistry & Applications

Department of Biomedical Sciences, University of Ngaoundéré, PO. Box 454, Ngaoundéré, Cameroon

Publications

• Research Article   
  Evaluation of the Acute and Sub-chronic Toxicity of the Ethanolic Extract of Curcuma longa (Zingiberaceae) in Wistar Albino Rats
  Author(s): Donatien Gatsing*, Gabriel Tchuente Kamsu, Simeon Pierre Chegaing Fodouop, Richard Simo Tagne, Norbert Kodjio and Adolette Lesly Nguelebek Fakam
  
  Background: Commonly called "two hundred diseases" in Western Cameroon, Curcuma longa is a plant widely used in traditional medicine for many years. In order to evaluate the safety of this plant commonly use in the treatment of typhoid fever in Cameroon, the acute and Sub-chronic toxicity of the ethanolic extract of Curcuma rhizomes has been studied in albino rats of Wistar strain. Materials and methods: Acute and sub-acute toxicity of this extract were study using OCDE 2008 guidelines. Results: The physical parameters were recorded during the experiment and the hematological and biochemical parameters, as well as the histology of the liver and reproductive organs were carried out at the end of the experiment. The acute toxicity study revealed no toxic effects, no behavioural disturbances an.. View more»
  

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