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Orkideh Hajipour
Department of Molecular Biology, Pamukkale University, Denizli, Turkey
Publications
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Research Article
Evaluating the Vaccine Potential of a Tetravalent Fusion Protein against Coronavirus (COVID-19)
Author(s): Mostafa Norizadeh Tazehkand* and Orkideh Hajipour
Coronaviruses are a type of viruses which cause illness ranging from the common cold to other diseases. SARS-CoV-2 is one coronaviruses family that cause respiratory syndrome. The virus first isolated from three people in Wuhan. This virus became known as COVID-19. Common signs of infection comprising of fever, respiratory symptoms, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death. There is not any vaccine for COVID-19. This study was aimed to design and analysis of recombinant cavvine against COVID-19. In this research the completely sequence of Envelope and Nucleocapsid protein was fused to multi epitopes (B and MHC I epitopes) obtained from Spike protein and RNA-dependent RNA polymerase and constructed a fusion vaccine. The vaccine has 621 .. View more»