Department of Pharmacy, Jashore University of Science and Technology, Jashore-7408, Bangladesh
Research Article
Evaluation of Medicinal Effects of Gynura Procumbens Leave Extracts On Oxidative, Glycemic, Lipidomics, and Enzymatic Profiles in Alloxan-Induced Diabetic Mice
Author(s): M. Ziaul Amin*, Mitu Afrin, Md. Ashaduzzaman Nur, Md. Mashiar Rahman and M. Jashim Uddin
To evaluate the medicinal impact of G. procumbens, this study designed to explore the anti-oxidant, anti-diabetic, anti-lipidemic, and enzyme activities of G. procumbens leaves extract.
Alloxan induced diabetic mice used for anti-diabetic activity. Blood was collected and analyzed glucose level, lipid profile, hepatic performance, renal activity, and oxidative stress emblem with different hours (1-5 hours) and days (7th -28th days) interval using standards protocol. Bioactive compounds like alkaloid, tannin, phenol, flavonoid, and terpenoid were present in the extracts. Anti-oxidant activities were evaluated at concentration of 15, 20, 25, 30, 35, 40 and 45 μg/mL but aqueous extracts showed very significant free radical scavenging activity at concentration 40 and 45 μg/mL, (**p>0.001). Both the aqueous and ethanolic extracts (GPLA.. View More»
DOI:
10.35248/2155-6156.21.12.876
