Journal of Stem Cell Research & Therapy

Journal of Stem Cell Research & Therapy
Open Access

ISSN: 2157-7633

+44 7456035580

Duygu Gülmez Sevim

Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey

  • Research Article   
    First Year Results of Subretinal Mesenchymal Stem Cell Implantation in Severe Retinitis Pigmentosa
    Author(s): Ayse Oner*, Z Burcin Gonen, Duygu Gülmez Sevim, Neslihan Sinim, Mustafa Cetin and Yusuf Ozkul

    This study includes one-year results of 14 patients with severe Retinitis Pigmentosa (RP) who had subretinal mesenchymal stem cell (ADMSC) implantation. The highest Visual Acuity (VA) in the study was 20/2000 and 7 of the patients had severe VA loss. The patients received subretinal ADMSCs after total vitrectomy. We observed no systemic complications. There were no ocular complications in 8 patients. Choroidal Neovascular Membrane (CNM) developed in one of the patients and intravitreal anti-VEGF injection was performed. The first six patients had Epiretinal Membrane (ERM) with peripheral tractional retinal detachment and received second vitrectomy. One of the patients experienced mild band keratopathy six months after the treatment and another patient had retrolental fibrous tissue at 1-year follow-up examination. Four patients showed VA gain during the first year. Subretinal .. Read More»
    DOI: 10.35248/2155-6156.19.9.454

    Abstract PDF