Journal of Allergy & Therapy

Journal of Allergy & Therapy
Open Access

ISSN: 2155-6121


Zohreh Tehranchinia

Zohreh Tehranchinia
Skin Research Center, Shohada-e Tajrish Hospital,
West Indies

  • Research Article
    Basal Serum Cortisol and Adrenocorticotropic Hormone Levels in Patients with Atopic Dermatitis
    Author(s): Zohreh Tehranchinia, Hoda Rahimi and Sara LotfiZohreh Tehranchinia, Hoda Rahimi and Sara Lotfi

    Background: Atopic dermatitis (AD) is an inflammatory skin disease with eczematous pruritic lesions. Topical corticosteroids are the most widely used and the mainstay of treatment for AD. There are some studies that percutaneous systemic absorption of topical steroids may occur and lead to suppression of hypothalamic-pituitaryadrenal axis (HPAA). However, almost in all of these studies, “basic” HPAA function (before application of topical steroids) was not evaluated. Aim: The aim of this study was to investigate basal serum cortisol, adrenocorticotropic hormone (ACTH), and IgE levels in patients with AD and their correlation with disease severity. Methods: Levels of basal serum cortisol, ACTH, and IgE were assessed by ELISA in 31 patients with AD and 31 control subjects. Clinical severity of AD was evaluated by the SCORAD (SCORing Atopic Dermatitis) index. Results: Data an.. Read More»
    DOI: 10.4172/2155-6121.1000236

    Abstract PDF

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