Zhen Sun
Bolivarian Rep. of Venezuela
Research Article
Cystatin C Versus Creatinine- Based Definition of Renal Dysfunction for Predicting Poor Coronary Collateralization in Type 2 Diabetic Patients with Stable Coronary Artery Disease
Author(s): Ying Shen, Feng Hua Ding, Feng Wu, Zhen Sun, Rui Yan Zhang, Qi Zhang, Lin Lu, Zong Gui Wu and Wei Feng ShenYing Shen, Feng Hua Ding, Feng Wu, Zhen Sun, Rui Yan Zhang, Qi Zhang, Lin Lu, Zong Gui Wu and Wei Feng Shen
Objective: Renal dysfunction represents a risk factor for poor coronary collateral growth. We investigated whether Glomerular Filtration Rate (GFR) estimated with the cystatin C-based formula (GFRCYS) is superior to that with the creatinine-based abbreviated Modification of Diet in Renal Disease (GFRMDRD) and the Chronic Kidney Disease Epidemiology Collaboration (GFREPI) equations for evaluating coronary collateralization in type 2 diabetic patients with stable coronary artery disease. Methods: GFR was estimated with creatinine- and cystatin C- based equations in 302 diabetic and 127 nondiabetic patients with stable angina and angiographic total occlusion of at least one major coronary artery. The degree of collaterals supplying the distal aspect of a total occlusion from the contra-lateral vessel was graded as poor (Rentrop score of 0 or 1) or good c.. View More»
