Journal of Stem Cell Research & Therapy

Ungkanont A

Publications

• Research Article
  Survival Benefit of Intravenous Busulfan (120 mg/M2) and Fludarabine Myeloablative Regimen for Treatment of Myeloid Malignancies
  Author(s): Niparuck P, Pukiat S, Puavilai T, Ativitavas T, Chantrathammachart P, Boonyawat K, Wacharapomin P, Angchaisuksiri P, Chuncharunee S, Jootar S, Atichartakarn V and Ungkanont ANiparuck P, Pukiat S, Puavilai T, Ativitavas T, Chantrathammachart P, Boonyawat K, Wacharapomin P, Angchaisuksiri P, Chuncharunee S, Jootar S, Atichartakarn V and Ungkanont A
  
  Background: Intravenous fludarabine and busulfan 130 mg/m2 (Flu/Bu) conditioning regimen has induced the long term survival with a low treatment related mortality rate. However, there have been few reports on long term survival of patients undergoing allo-HSCT with intravenous Flu/Bu regimen. Therefore, we conducted a retrospective study of 42 patients diagnosed with myeloid malignancies received allo-HSCT with intravenous fludarabine and busulfan (120 mg/m2) regimen between 2006 and 2015 at Ramathibodi hospital. The aim of our study was to observe the long term survival and the complication after transplantation. Findings: Thirty- four, three and five patients were AML, MDS and CML-CP respectively. With a median followup of 95 months, 1- year EFS and 8- year EFS were 82 and 70% respectively. Overall survival (OS) rate at 1 and.. View More»
  DOI: 10.4172/2157-7633.1000338

  Abstract PDF