PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Genamics JournalSeek
- JournalTOCs
- Ulrich's Periodicals Directory
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Proquest Summons
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Ulf Schött
Ulf Schött
Skane University Hospital, Department of Anaesthesiology and Intensive Care, S-22185, Lund
Sweden
Publications
-
Research Article
Effects of High Dose Fibrinogen on in vitro Haemodilution with Different Therapeutic Fluids
Author(s): Eric Lidgard, Attila Frigyesi and Ulf SchöttEric Lidgard, Attila Frigyesi and Ulf Schött
Background: Therapeutic fluids used in intensive care can have profound effects on coagulation, not only by dilution itself but also by other more complicated interactions. The aim of this in vitro study was to monitor the extent of dilutive coagulopathy induced by the most common therapeutic fluids and to attempt normalization of haemostasis by fibrinogen addition. Methods: 8 patients were recruited from the intensive care unit. Native whole blood was drawn, diluted by 50% with 9 different fluids, and run through a Sonoclot Analyzer. This was then repeated with high dose fibrinogen (corresponding to an in vivo dose of 8g/70kg) added to the dilutions. The fluids used were Voluven, Venofundin, Volulyte, Tetraspan, Albumin 5%, Macrodex, Gelofusine, Ringer’s acetate and NaCl. This covers the entire spectrum of fluids available in Sweden. Results: A significant i.. View More»
DOI: 10.4172/2155-9864.1000106