Journal of Blood Disorders & Transfusion

Uche Okonkwo

Publications

• Research Article
  Disease Severity Scores and Haemogram Parameters in Nigerian Sickle Cell Disease Patients
  Author(s): Emmanuel Okocha, Emmanuel Onwubuya, Charles Osuji, Gladys Ahaneku, Uche Okonkwo, Nancy Ibeh, John Aneke, Ebele Nwachukwu and Christian OnahEmmanuel Okocha, Emmanuel Onwubuya, Charles Osuji, Gladys Ahaneku, Uche Okonkwo, Nancy Ibeh, John Aneke, Ebele Nwachukwu and Christian Onah
  
  Background: Sickle cell disease (SCD) is associated with high mortality in Nigeria and the rest of sub-Saharan Africa; there is need to find easily available parameters that could predict disease severity and influence therapy. Objective: To evaluate the haemogram of a population of SCD patients and correlate these with objective scores of disease severity. Methods: Sixty (60) asymptomatic steady state (ASS) SCD patients in our clinic were randomly selected and interviewed with a questionnaire. Their haemogram was done using a 17 parameter, 3-part white cell differential, auto-analyser (KX 21N, Sysmex corporation, Chuo ku, Kobe, Japan) and objective severity scores calculated using a modification of the method proposed by Anyeagbu et al. Statistical analysis of data was done using Statistical Package for Social Sciences software, version 20 (SPSS Inc., IL, Chicago, USA.. View More»
  DOI: 10.4172/2155-9864.1000324

  Abstract PDF