Journal of Thrombosis and Circulation: Open Access

Journal of Thrombosis and Circulation: Open Access
Open Access

ISSN: 2572-9462

+44 7460731551

Tsai HM

Tsai HM


  • Research Article
    HIV Infection Increases the Risk of Thrombotic Thrombocytopenic Purpura
    Author(s): Dobson CE and Tsai HMDobson CE and Tsai HM

    An association between HIV infection and Thrombotic Thrombocytopenic Purpura (TTP) remains controversial.We conducted a cross-sectional analysis of 39 consecutive, non-referral cases of TTP encountered over 9 years ata single institution. Thirteen cases had HIV infection. The patients were treated with daily plasma exchange untilremission. The mean (standard deviation) duration of follow-up was 48 (37) months. Seven patients died. TTPcaused 3 of the 4 deaths in the HIV- group but none of the 3 deaths in the HIV+ groups. The age and sex adjustedincidence rate of TTP was 14.5 cases per 106 person-years. The relative risk of TTP was 38.5 (95% confidenceinterval, 19.7-75.0) for HIV infection, 2.7 (1.3-5.7) for female gender and was not increased for the black race.Neither HIV infection nor gender affect the overall and relapse free survivals. While relapse continued to occurthroughout the.. Read More»
    DOI: 10.4172/2572-9462.1000127

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