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Tiwari M
Tiwari M
India
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Review Article
Significances of OMV and Extracellular Vesicle Proteomics
Author(s): Tiwari V, Solanki V, Roy R, Biswas D and Tiwari MTiwari V, Solanki V, Roy R, Biswas D and Tiwari M
Outer Membrane Vesicle (OMV) proteome has been involved into the pathogenesis of diseases and resistance of microorganisms against a number of antibiotics, mechanism of action of probiotics and host-pathogen interaction etc. We have enlightened the role played by extracellular vesicles proteomics in the pathogenesis of different diseases related to human. Isolation succeeded by purification of ample amount of OMV from biological samples, is one of the most important steps for further proteome related analysis. With the development of both labelled and label-free methods used in proteomics, significant progress has been made in previous years in membrane proteomics. Hence, it is important to review the biological significance of proteins found in the OMV fractions using membrane proteomics approach. We have also explained methods used for isolation, purification and quantification of O.. View More»
DOI: 10.4172/2153-0602.1000208