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Thaís Mendes-Lopes
ThaÃs Mendes-Lopes
Brazil
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Research Article
High Prevalence of Esophageal Acid Exposure in Very Low Birth Weight Infants Presenting or Not Bronchopulmonary Dysplasia: A Prospective Cross-Sectional Study
Author(s): ThaÃs Mendes-Lopes, José Dirceu Ribeiro and Maria Aparecida MezzacappaThaís Mendes-Lopes, José Dirceu Ribeiro and Maria Aparecida Mezzacappa
Background: A high frequency of treatment for gastroesophageal reflux disease is observed in neonates with Bronchopulmonary Dysplasia (BPD). The association between these illnesses is controversial. Objective: To determine the prevalence of reflux index ≥ 10%, in very low birth weight infants, presenting or not BPD, using esophageal pH monitoring. Methods: A prospective cross-sectional study was conducted. Thirty-five newborns presenting BPD and 15 newborns not presenting BPD underwent distal esophageal pH monitoring during their stay in a university hospital neonatal unit. The frequency of symptoms and gastroesophageal reflux treatment was studied in both groups. Results: The prevalence of reflux index ≥ 10% did not differ between groups presenting (65.7%) and not presenting BPD (93.3%); p=0.075. Symptoms attribut.. View More»
DOI: 10.4172/2167-0897.1000127