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Tejpreet Chadha
Tejpreet Chadha
Texas Technological University,
Lubbock, Texas
Tanzania
Publications
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Research Article
Motility and β-Lactamases: Occurrences of Antibiotic Resistance in Nosocomial Infections
Author(s): Tejpreet Chadha and John. C. ZakTejpreet Chadha and John. C. Zak
The widespread use of β-lactam antibiotics has resulted in the global emergence of antibiotic-resistant bacterial strains. Multidrug resistant isolates are now more difficult to treat due to multiple intrinsic and acquired mechanisms of drug resistance that operate simultaneously in a bacterial cell. Motility is associated with virulence that contributes to multidrug resistance. The current analysis has shown that natural pattern of distribution of Ambler (molecular) classes of β-lactamases (A, B, C, D) varied among motile and non-motile nosocomial pathogens. Our results revealed that the relative abundance of class A β-lactamases was highest in bacterial species that are non-motile. However, the relative abundance of class C β-lactamases was mostly same for both motile and non-motile bacterial species. The class D β-lactamases was found highest in bacterial s.. View More»
DOI: 10.4172/2153-0602.1000126