Journal of Blood Disorders & Transfusion

Tamaddon Gholamhossein

Publications

• Research Article
  Prevalence of Alloimmunization against RBC Antigens in Thalassemia Major Patients in South East Of Iran
  Author(s): Mirzaeian Amin, Tamaddon Gholamhossein, Naderi Majid, Hosseinpour Marziyeh, Sargolzaie Narges, Dorgalaleh Akbar and Tabibian ShadiMirzaeian Amin, Tamaddon Gholamhossein, Naderi Majid, Hosseinpour Marziyeh, Sargolzaie Narges, Dorgalaleh Akbar and Tabibian Shadi
  
  Background: Thalassemia major is a lifelong transfusion dependent disease. Continuous blood transfusion can causes alloimmunization against RBC antigens and complicate further treatment in these patients. The purpose of this study was to determine the frequency of RBC allo and auto antibodies, the types of these antibodies and the factors that affect alloimmunization in patients with thalassemia. Material and methods: This descriptive study was performed on 221 males and 164 females with thalassemia major referred to Ali Asghar hospital in Zahedan, Iran. Initially information sheet about age, gender, race, age on first blood transfusion, history of splenectomy and ABO & Rh blood group were filled out. For alloantibody screening, patients serum were tested in three phases (Salin, 37°C with LISS and Anti Human Globulin ) by pooled cell.. View More»
  DOI: 10.4172/2155-9864.1000147

  Abstract PDF