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Susmita Singh
Susmita Singh
UGC Dr. D. S. Kothari Post- Doctoral Fellow, Department of Molecular Biology and Biotechnology, Tezpur University, Napaam-784028, Assam,
India
Publications
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Review Article
L-Amino Acid Oxidases-Microbial and Snake Venom
Author(s): Susmita SinghSusmita Singh
L-amino acid oxidases (EC 1.4.3.2, L-aao) are flavoenzymes that catalyse the stereospecific deamination of an L-amino acid to their corresponding α-keto acid with the production of hydrogen peroxide and ammonia. These enzymes are widely distributed across diverse phyla from bacteria, fungi to mammals and many venomous snakes. Although they are mainly involved in cellular amino acid catabolism, many other physiological functions are attributed to L-aao including their antibacterial property and ability to protect from infection. L-aao has also been correlated with penicillin production, violacein synthesis and biofilm development and cell dispersal. Snake venom L-aaos are studied extensively for their ability to induce apoptosis, aggregate platelets, induce haemorrhage, edema and many other toxic effects. L-aaos have been characterized biochemically and found to differ in terms o.. View More»
DOI: 10.4172/1948-5948.1000133