Journal of Pharmacovigilance

Sivaprakash B

Publications

• Research Article
  Hyponatremia Secondary to Antidepressant Therapy - A Post Marketing Safety Study
  Author(s): Harsha M Shetty, Manimekalai K, Sivaprakash B, Jagan Mohan R and Pooja H ShettyHarsha M Shetty, Manimekalai K, Sivaprakash B, Jagan Mohan R and Pooja H Shetty
  
  Background: Most antidepressants have been associated with hyponatremia. The risk is highest during the early stages of the treatment. Symptoms are commonly mistaken for physical complaints of old age or the underlying conditions. Speed of onset determines the risk of developing symptoms. Aims and Objectives: To establish the incidence, risk factors, time course of detection of hyponatremia complicating treatment with antidepressant therapy. Also, to objectively assess the causality, severity and preventability of hyponatremia as an adverse drug reaction. Methods: The study was carried out in collaboration between the Departments of Pharmacology and Psychiatry, Mahatma Gandhi Medical College and Research Institute, India. The source .. View More»
  DOI: 10.4172/2329-6887.1000167

  Abstract PDF