Clinical Microbiology: Open Access

Santosh Pandit

Publications

• Short Communication
  Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms
  Author(s): Santosh Pandit, Mokkapati VRSS, Saga Huld Helgadóttir, Fredrik Westerlund and Ivan MijakovicSantosh Pandit, Mokkapati VRSS, Saga Huld Helgadóttir, Fredrik Westerlund and Ivan Mijakovic
  
  Cold atmospheric plasma (CAP) is increasingly used in medical applications for eradication of bacterial and tumor cells. CAP treatment devices, known as plasma jet pens, produce reactive oxygen and nitrogen species at atmospheric pressure and room temperature. The produced reactive species are concentrated in a small and precisely defined area, allowing for high precision medical treatments. CAP has been demonstrated as very effective against planktonic bacterial cells. Unfortunately, bacterial cells in biofilms are typically aggregated and protected by dense exopolymeric matrix, synthesized and secreted by the bacterial community. The main limitation in using CAP against bacterial biofilms is the thick protective matrix of extracellular polymers that shields bacterial cells within this complex architecture. CAP has also been shown to effectively eradicate tumor cells, but the main cu.. View More»
  DOI: 10.4172/2327-5073.1000283

  Abstract PDF