Clinical Microbiology: Open Access

Sai-zhen Zhen

Publications

• Research Article
  Clinical Epidemiological and Pathogenic Analyses for Acute Viral Infections of Central Nervous System in Hospitalized Children of Hunan Province, China
  Author(s): Bing Zhang, Tian Yu, Yi-min Zhu, Jie Xiong, Sai-zhen Zhen and Tao WangBing Zhang, Tian Yu, Yi-min Zhu, Jie Xiong, Sai-zhen Zhen and Tao Wang
  
  Background: Virus infection of the central nervous system is a common disease in children. The major causes of ineffective therapy are misdiagnosis and delayed interventions. Based upon our pilot study, consecutive specimens of cerebrospinal fluid were collected and detected. Methods: From October 2012 to July 2014, a total of 161 cerebrospinal fluids samples were collected from the patients with a clinical diagnosis of viral encephalitis at our hospital. The technique of real-time fluorescence quantitative-polymerase chain reaction was employed. Results: Viruses were detected in 71 cases with an overall detection rate of 44.10%. In our cohort, the average viral load was 198.24 ± 993.61 copies/μL. And the viral loads had no obvious correlations with hospitalization duration. Enterovirus had the highest detectio.. View More»
  DOI: 10.4172/2327-5073.1000306

  Abstract PDF