Ruffo A
University “Federico II’’ of Naples Via S. Pansini,
5 – 80131 Naples
Italy
Research Article
Treating Idiopathic Male Infertility with a Combination of Tamoxifen
Citrate and a Natural Compost with Antioxidant and Androgen-Mimetic
Action
Author(s): Iacono F, Prezioso D, Ruffo A, Di Lauro G, Illiano E, Romeo G and Romis LIacono F, Prezioso D, Ruffo A, Di Lauro G, Illiano E, Romeo G and Romis L
Background: We investigated the efficacy of a combination therapy with tamoxifen citrate and a natural composite containing Tribulus terrestris, alga Ecklonia bicyclis and polymers of d-glucosamine and n-acetyl d-glucosamine in treating male idiopathic infertility.
Methods: In this prospective, randomized double blind, placebo-controlled study, we enrolled ninety infertile men at our department of urology at University Federico II of Naples. Mean age was 29.2 ± 7.8 [± SD]. Inclusion criteria consisted of the repeated exhibition of oligoasthenozoospermia (OA) without detectable cause (unexplained OA). Patients were randomly assigned to three treatment groups: Group A (n=30) receiving tamoxifene citrate (20 mg/day) and a natural composite with an antioxidant and androgen-mimetic action (150 mg of alga Ecklonia Bicyclis, 396 mg of.. View More»
