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PR Raghavan
PR Raghavan
Nanorx Inc, PO Box 131, Chappaqua, NY 10514
Tanzania
Publications
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Research Article
Improving Longevity with Metadichol® by Inhibiting the BCAT1 Gene
Author(s): PR RaghavanPR Raghavan
Metadichol® [1] is a Nanoemulsion of long-chain alcohols found in many foods. It is commonly called Policosanol and is present in foods such as rice, sugar cane, wheat, peanuts Metadichol acts as an inverse agonist on Nuclear Vitamin D receptors (VDR) that are present in cells throughout the body to stimulate the immune system and affects many biologIcal processes to modulate many diseases. Branched-chain amino acid transferase (BCAT1) catalyzes the reversible transamination of leucine, isoleucine, and valine branched-chain amino acids (BCAA) to their respective alpha-keto acids, liberating L-glutamate. When this gene is inhibited, the amino acid chains accumulated in the tissue triggering longevity in the nematodes. The health and longevity of the nematodes improved when BCAT1 was inhibited. Gabapentin has been shown to inhibit BCAT1, but IC50 is 10000 uM. Metadichol&re.. View More»
DOI: 10.4172/2329-8847.1000174