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Piotr Dobrowolski
Piotr Dobrowolski
Poland
Publications
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Research Article
Maternal Nutrition with ÃŽÂ’-Hydroxy-ÃŽÂ’ Methylbutyrate as Strong Determinants of the Development of Newborn Offspring in Pigs
Author(s): Ewa Tomaszewska, Piotr Dobrowolski, Monika Hulas-Stasiak and Agnieszka TomczykEwa Tomaszewska, Piotr Dobrowolski, Monika Hulas-Stasiak and Agnieszka Tomczyk
Aim: Interferences into maternal nutrient are used in studies related to prenatal programming - permanent changes in homeostasis of regulatory physiological mechanisms. Thus, the effect of HMB (β-Hydroxy-β-methylbutyrate) maternal administration on body characteristic in newborn offspring was studied. Methods: Sows were fed with a standard diet and diet supplemented with HMB (0.2 mg/kg of body weight/ every day) in the morning meals from 70th to 90th day of gestation. Twenty four newborn piglets were weight and euthanized, organ weights were recorded. Moreover, changes in the somatotropin axis were assessed by determination of insulinlike growth factor 1. Results: Maternal HMB supplementation significantly affected weight at birth. The weight of the liver was increased by 160% in the HMB piglets (P < 0.01) compared with Cont piglets, and the spleen was 67% heavier.. View More»
DOI: 10.4172/2167-0897.1000183