Journal of Pharmacovigilance

Peter Lakatos

Publications

• Research Article
  Safety and Efficacy of Weekly 30,000 IU Vitamin D Supplementation as a Slower Loading Dose Administration Compared to a Daily Maintenance Schedule in Deficient Patients: A Randomized, Controlled Clinical Trial
  Author(s): Bela E Toth, Istvan Takacsb, Laszlo Szekeresc, Boglarka Szabo, Bence Bakos and Peter LakatosBela E Toth, Istvan Takacsb, Laszlo Szekeresc, Boglarka Szabo, Bence Bakos and Peter Lakatos
  
  Introduction: The primary objective of the study was to assess the safety and the efficacy of a “Slower Loading” dose of 30,000 IU vitamin D3 supplementation administered in a weekly schedule for 12 weeks in vitamin D deficient patients compared to the daily equivalent dose of 1000 IU/day regimens in a clinical trial. Methods: This open label, randomized, controlled, multicenter clinical trial was performed during the spring and summer period enrolling adult subjects with 25O HD levels <20 ng/ml. In a sub-study presented here, subjects were randomized into two treatment groups using 30,0000 IU Vitamin D3 film tablets either in weekly (WD30K group, daily dose equivalent of 4286 IU/day) or a standard dose for maintenance treatment in a daily administration (SDD1K group, 1000 IU/day). Subjects in a control group received a simila.. View More»
  DOI: 10.4172/2329-6887.1000233

  Abstract PDF