Journal of Data Mining in Genomics & Proteomics

Palit EIY

Publications

• Research Article
  The Highest Mutation in mtDNA Hypervariable Region and Application of Biostatistics with Nucleotide Base X _t-n in Determining the Identity of the Mutation through a Transition Intensity Matrix
  Author(s): Palit EIY and Ngili YPalit EIY and Ngili Y
  
  Human mitochondrial DNA (mtDNA) have been used intensively in the field of forensic identification of victims or suspects of crime through biological evidence. The number of mtDNA molecules in a single cell are in the tens of thousands which enable analysis of samples very little or damaged. Till now there is no standard method for identification using mtDNA in a mass disaster victims such as natural disasters, wars and accidents so that the identification process can not run fast. This study found C16.223t variants in mtDNA sequences that can be used to divide the database into two groups so as to accelerate the process of identification through a mathematical algorithm. This variant has the highest frequency (29.7%) of the 91 polymorphic human mtDNA HVS1 along the 300 nucleotide (16,024-16,324) derived from the NCBI database as much as 142 sequences. MtDNA sequences obtained from da.. View More»
  DOI: 10.4172/2153-0602.1000213

  Abstract PDF