Indexed In
- Open J Gate
- Genamics JournalSeek
- CiteFactor
- Cosmos IF
- Scimago
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- Directory of Abstract Indexing for Journals
- OCLC- WorldCat
- Proquest Summons
- Scholarsteer
- ROAD
- Virtual Library of Biology (vifabio)
- Publons
- Geneva Foundation for Medical Education and Research
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Palayakotai R Raghavan
Palayakotai R Raghavan
Nanorx Inc,
Po Box 131, Chappaqua, NY 10514
Tanzania
Publications
-
Research Article
Metadichol®, Vitamin C and GULO Gene Expression in Mouse Adipocytes
Author(s): Palayakotai R RaghavanPalayakotai R Raghavan
Metadichol, a novel nano emulsion of lipid alcohols, up regulates the expression of GULO gene in mouse at picogram levels. 3T3-L1 pre adipocyte cells were differentiated using differentiating media. Post differentiation, the cells were treated with different concentrations of Metadichol for 24 hours and untreated cells served as control. Whole RNA was isolated after the treatment period and semi-quantitative reverse transcription PCR was run with GULO gene specific primer to obtain cDNA. Relative gene expression of GULO was determined by analysis of GULO gene amplicons using image J software. The GULO gene expression in the treated cells was up regulated fourfold relative to basal level of untreated cells.. Relative gene expression at concentrations 1 μg/ml, 100 ng/ml, 1 ng/ml, 100 pg/ml, 1 pg/ml was found to be 2.11, 2.64, 2.96, 3.96,.. View More»
DOI: 10.4172/0974-8369.1000426