Journal of Stem Cell Research & Therapy

Palak Shah

Publications

• Review Article
  Cardiovascular Applications of Stem Cell Therapy
  Author(s): Soheil Sadri, Ramesh Mazhari, Maziar Sadri, Nahal Konjedi and Palak ShahSoheil Sadri, Ramesh Mazhari, Maziar Sadri, Nahal Konjedi and Palak Shah
  
  Despite remarkable progress in medical and surgical therapy for heart disease, congestive heart failure (CHF) and coronary artery disease (CAD) are leading causes of morbidity and mortality in the United States. Although implantation of a left ventricular assist device has recently emerged as a promising therapy for CHF, no other therapy holds as much promise for the treatment of patients suffering from cardiovascular disease other than cardiac regeneration. In this regard, there are substantial pre-clinical and clinical studies that have elucidated the safety and efficacy of cardiac stem cell-based therapy using a variety of cell lines to promote regeneration of the heart. In spite of promising results in both animal and human studies, the exact fate of these administered stem cells within the human heart is poorly understood as is the mechanism by which they promote myocardia.. View More»
  DOI: 10.4172/2157-7633.S1-003

  Abstract PDF