Review Article
Incidence and Correlates of Hypoglycemia in Type 2 Diabetes. The Hypos-1 Study
Author(s): Carlo B Giorda, Alessandro Ozzello, Sandro Gentile, Andrea Corsi, Rossella Iannarelli, Fabio Baccetti, Giuseppe Lucisano, Antonio Nicolucci, Maria Chiara Rossi and On behalf the HYPOS-1 Study GroupCarlo B Giorda, Alessandro Ozzello, Sandro Gentile, Andrea Corsi, Rossella Iannarelli, Fabio Baccetti, Giuseppe Lucisano, Antonio Nicolucci, Maria Chiara Rossi and On behalf the HYPOS-1 Study Group
Background: To evaluate the incidence of severe and symptomatic hypoglycemia in type 2 diabetes and identify their correlates.
Materials and methods: HYPOS-1 is an observational retrospective study. Socio-demographic and clinical characteristics, experience of severe hypoglycemia in the past 12 months and experience of symptomatic hypoglycemia in the past 4 weeks were recorded through a patient questionnaire and a clinical record form. Poisson multivariate models were applied.
Results: Overall, 2023 patients were involved by 18 diabetes clinics. Incidence rate (IR) of severe hypoglycemia was of 0.09 events/person-years; IR of symptomatic hypoglycemia was of 9.30 events/person-years. A minority of patients accounted for the vast majority of severe episodes. The risk of severe hypoglycemia was three times higher in patients with previous severe (Inci.. View More»
