Cardiovascular Pharmacology: Open Access

Cardiovascular Pharmacology: Open Access
Open Access

ISSN: 2329-6607

Mushtaq N

Mushtaq N


  • Research Article
    Gender Based Compositional Fluctuations in Gut Microbiota in Hypertension
    Author(s): Mushtaq N, Hussain S, Yuan L, Zhang S, Li H, Ullah S and Xu JMushtaq N, Hussain S, Yuan L, Zhang S, Li H, Ullah S and Xu J

    Background: Emerging evidence suggests that human gut microbiota plays a critical role in maintaining physiological homeostasis, and gut dysbiosis is involved directly or indirectly in cardiovascular diseases including hypertension. Aim: The aim of the present study was to investigate whether there were sex-based compositional differences in gut microbiota of patients with hypertension. Methods: Fecal samples were collected from male and female hypertensive patients, and healthy individuals from Xi’an, Shaanxi province of China. Touchdown PCR and denaturing gradient gel electrophoresis (PCR-DGGE) with primers specifically targeting V3 region of 16S rRNA, and real-time quantitative PCR (qPCR) were performed to characterize all the samples. High-throughput sequencing of the V3–V4 regions was performed on Illumi.. Read More»
    DOI: 10.4172/2329-6607.1000248

    Abstract PDF

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