Modern Chemistry & Applications

Moussa Madany Moustafa

Publications

• Research Article
  Evaluation of Carbonylated Proteins in Hepatitis C Virus Patients
  Author(s): Mahmoud Mohamed Alou-El-Makarem, Moussa Madany Moustafa, Mohamed Abdel-Aziz Fahmy, Aamer Mohamed Abdel-Hamed, Khaled Nagy El-fayomy and Medhat Mohamed Abdel-Salam DarwishMahmoud Mohamed Alou-El-Makarem, Moussa Madany Moustafa, Mohamed Abdel-Aziz Fahmy, Aamer Mohamed Abdel-Hamed, Khaled Nagy El-fayomy and Medhat Mohamed Abdel-Salam Darwish
  
  Carbonylated proteins are irreversible posttranslational oxidative modifications, which may interfere with the normal homeostasis of cell growth inducing liver cirrhosis and risk of malignancy. Objective: To determine plasma levels of carbonylated proteins and total antioxidant capacity and evaluate their role in HCV hepatitis patients and HCV induced liver cirrhosis before and after antiviral therapy; interferon and ribavirin. Methods: This study included twenty chronic hepatitis C patients with cirrhotic changes, twenty chronic hepatitis C patients without cirrhotic changes and before taking interferon therapy and Fifteen chronic hepatitis C patients without cirrhotic changes and after taking antiviral therapy; interferon (PEG-IFN α2a 180-μg/week and Ribavirin 800 mg capsule one time daily for 24 weeks). Twenty male healthy.. View More»
  DOI: 10.4172/2329-6798.1000130

  Abstract PDF