Mohamed Abo El Asrar
Egypt
Research Article
Serum and Urinary Nitrites and Nitrates and Doppler Sonography in Detection of Early Diabetic Complications
Author(s): Mohamed Abo El Asrar, Amira A.M. Adly, Eman El Hadidi and Mohamed GharibMohamed Abo El Asrar, Amira A.M. Adly, Eman El Hadidi and Mohamed Gharib
Objective: to evaluate serum and urinary nitrite and nitrate concentrations as an index of nitric oxide (NO) production in type1diabetes mellitus (T1DM) and to investigate the possible alteration and correlation with intra renal Doppler resistive indexes (RIs). Design: The study included 90 children and adolescent with T1DM divided into 2 groups: Group 1: included 45 prepubertal type1 diabetics who were defined as Tanner stage1. Their age ranged between 8-14 years. Group 2: included 45 pubertal type diabetics who were defined as Tanner stages 2-5. Their ages ranged between 15-19 years. They were compared to 45 age and sex matched healthy controls. Clinical examination was done. Laboratory investigations included; post-prandial blood glucose (PPBG), glycosylated heamoglobin (HbA1C), Fundus examination, urinary microalbumin and measurement of serum and urinary nitrite and nitrate leve.. View More»
