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Mihnea-Alexandru Gaman
Mihnea-Alexandru Gaman
Romania
Publications
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Research Article
Immune Thrombocytopenia in Chronic Lymphocytic Leukemia
Author(s): Amelia Maria Gaman and Mihnea-Alexandru GamanAmelia Maria Gaman and Mihnea-Alexandru Gaman
Introduction: Chronic lymphocytic leukemia (CLL) is a malignant proliferation of mature, differentiated B-lymphocytes associated in 1-5 % of cases with immune thrombocytopenia (ITP). The effect of ITP on the clinical outcome and survival of patients with CLL is controversial. Materials and methods: The aim of the study was to evaluate the level of oxidative stress in patients with CLL and ITP and how this complication influences the patient’s survival. We studied 84 patients with CLL hospitalized in the Clinic of Hematology from Craiova (Romania) between 2007 and 2012 .The global oxidative status at diagnosis of CLL and in the presence of ITP by FORT (Free Oxygen Radicals Testing) and FORD (Free Oxygen Radical Defence) tests and the median overall survival in patients with CLL - stage C immune disease compared to stage C-infiltrative disease were evaluated. R.. View More»
DOI: 10.4172/2155-9864.1000198