Michael C. Riddell
Canada
Research Article
Differences in the Association between Clinically Relevant Classifications of Glycemia Measures and All-Cause and Cardiovascular Disease Mortality Risk
Author(s): Jacinta I. Reddigan, Chris I. Ardern, Michael C. Riddell and Jennifer L. KukJacinta I. Reddigan, Chris I. Ardern, Michael C. Riddell and Jennifer L. Kuk
Aims: To examine all-cause and cardiovascular disease (CVD) mortality risk in individuals categorized as normal, impaired or type 2 diabetic using clinical cutoffs for fasting plasma glucose (FPG), 2-hour plasma glucose (2hPG) and glycated hemoglobin (HbA1c).
Methods: The sample included 5,424 adults with undiagnosed diabetes from the Third National Health and Nutrition Examination Survey with public-access mortality data linkage (follow-up=8.5 ±2.3 years; 685 deaths). The association between the glycemic measures and all-cause and CVD mortality were analyzed with the measures as continuous and categorical variables. FPG, 2hPG and HbA1c were categorized using the American Diabetes Association criteria for normal, impaired and type 2 diabetes.
Results: When analyzed as a continuous variab.. View More»
