Marlen I. Castellanos
Calle 25 No.503 e/ H e I. Vedado. CP 10400.
Plaza de la Revolución, La Habana
Immune Alterations in Liver Cirrhosis: Its Relationship with Etiology,Child Pugh Stage and Malnutrition
Author(s): Marlen I. Castellanos, Osvaldo R. Seijas, Dayamí González, Mercedes Ronquillo, Maria del Rosario Abreu and Sergio OjedaMarlen I. Castellanos, Osvaldo R. Seijas, Dayamí González, Mercedes Ronquillo, Maria del Rosario Abreu and Sergio Ojeda
Background: Immune alterations in liver cirrhosis are variable and only a few have been correlated with the severity of the disease, malnutrition or its etiology. Methods: A descriptive transversal study was carried out in 76 patients with liver cirrhosis predominantly of viral cause. According to the Child Pugh stage they were classified in A: 52, B:17 and C: 7. The anthropometric evaluation included mid-arm circumference, triceps and subscapular skinfold thickness. The humoral immune alterations were evaluated by assessing serum immunoglobulin (A, M, G and E) and the complement components’ C3 and C4. Cellular immunity integrated a total lymphocyte count and the delayed intradermal hypersensitivity test. The statistical analysis included Pearson’s Chi squared and non-parametric tests using the U Mann Whitney or Kruskal Wallis te.. Read More»