Journal of Nutritional Disorders & Therapy

Maria Giannì

Publications

• Research Article
  Microbial and Immune Biomarkers in Infants at Risk for Allergies Fed an Intact Cows Milk Formula Containing Specific Non-Digestible Carbohydrates
  Author(s): Karen Knipping, Anna Orsi, Günther Boehm, Francesca Castoldi, Johan Garssen, Maria Giannì, Tom Groot Kormelink, Gianluca Lista, Paola Marangione, Frank Redegeld, Paola Roggero and Fabio MoscaKaren Knipping, Anna Orsi, Günther Boehm, Francesca Castoldi, Johan Garssen, Maria Giannì, Tom Groot Kormelink, Gianluca Lista, Paola Marangione, Frank Redegeld, Paola Roggero and Fabio Mosca
  
  Background: Oligosaccharides may support postnatal immune development by influencing the constitution of gastrointestinal microbiota. This prospective, double-blind, randomised, placebo controlled trial investigated the effect of a specific prebiotic mixture of short chain galactooligosaccharides (scGOS) and long chain fructooligosaccharides (lcFOS) on microbiota and immune biomarkers during the first six months of life in high risk infants for allergies fed a formula based on intact cow’s milk protein. Methods: If formula feeding was started, the infant was randomly assigned to one of two cow’s milk formula groups (0.8 g/100 ml scGOS/lcFOS or maltodextrine as control). The faecal microbiota of the scGOS/lcFOS and control groups was analysed. In a subgroup blood was collected at the age of six months for serum biomarkers. A refer.. View More»
  DOI: 10.4172/2161-0509.1000119

  Abstract PDF