Journal of Allergy & Therapy

Journal of Allergy & Therapy
Open Access

ISSN: 2155-6121

Marcello Mincarini

  • Review Article
    Allergen Specific Immunotherapy in Asthma
    Author(s): Marcello Mincarini, Anthi Rogkakou, Francesco Balbi and Giovanni PassalacquaMarcello Mincarini, Anthi Rogkakou, Francesco Balbi and Giovanni Passalacqua

    The use of allergen Specific Immunotherapy (SIT) to treat allergic asthma is still a matter of scientific debate. Currently, there are few studies specifically designed to evaluate asthma, and few studies had a formal sample size calculation, or objective parameters of pulmonary function assessed. On the other hand, there are good quality trials with both Subcutaneous Immuno-therapy (SCIT) and Sublingual Immunotherapy (SLIT) in allergic rhinitis, where asthma symptoms were also evaluated, if present. These studies consistently reported positive results. Moreover, several favourable meta-analyses are available, although their validity is limited by the great heterogeneity of the trials included. The disease modifying effect of SIT that is the capacity of preventing asthma onset should be also taken into account. Concerning the safety, fatalities seem to be an exceptional even.. Read More»
    DOI: 10.4172/2155-6121.1000190

    Abstract PDF

Relevant Topics