Journal of Stem Cell Research & Therapy

Journal of Stem Cell Research & Therapy
Open Access

ISSN: 2157-7633

+44 7456 035580

Mansy A

Mansy A

Egypt

Publications
  • Research Article
    Therapeutic Potential of Mesenchymal Stem Cells and Vitamin E on Experimental Hepatocellular Carcinoma
    Author(s): Ragaei A, Mansy A and Sabry DRagaei A, Mansy A and Sabry D

    Purpose: This study evaluated the influence of human mesenchymal stem cells (h-MSCs) and/or vitamin E (vit E) on experimental hepatocellular carcinoma (HCC). Methods: Eighty five rats were divided into; group 1: twenty rats served as control group and group 2: sixty five rats received Diethyl Nitrosamine (DENA) followed by carbon tetra chloride (CCl4) to induce HCC. Five rats were scarified after 2 months to assess the induction of HCC. The other sixty rats were further subdivided into; group 2: fifteen HCC were untreated rats, group 3: fifteen HCC rats were treated by injection of 107 h-AMSCs, group 4: fifteen HCC rats were treated by vitamin E and group 5: fifteen HCC rats were treated by injection of 107 h-AMSCs and vitamin E. Histological, arginase-1 immunohistochemical examination were assessed and serum albumin and α-fetoprotein were estimated. Results: Histopathological e.. Read More»
    DOI: 10.4172/2157-7633.1000362

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