Biology and Medicine

Manoth Kumer Biswas

Publications

• Research Article
  Evaluation of Pharmacological and Toxicological Studies of Ayurvedic Medicine Siddha Makardhwaja on Biological System of Male Sprague-Dawley Rats
  Author(s): Md. Mamun Sikder, Nilay Saha, Umma Hafsa Asha, Md. Nuruzzaman Neon, Khadija Akter, Manoth Kumer Biswas, Md. Rakib Hasan and M. S. K. ChoudhuriMd. Mamun Sikder, Nilay Saha, Umma Hafsa Asha, Md. Nuruzzaman Neon, Khadija Akter, Manoth Kumer Biswas, Md. Rakib Hasan and M. S. K. Choudhuri
  
  In this study, the pharmacological and toxicological effects along with possible side effects of the classical ayurvedic formulation Siddha Makardhwaja (SMD) which is used as a traditional medicine in the treatment in the rural population were evaluated. During this study, various experiments on organ body weight ratio and tissue hydration indices were performed to evaluate its effi cacy and toxicity. SMD was administered chronically to the male Sprague-Dawley rats at a dose of 40 mg/kg to determine its toxicological characteristics. After 28 days of chronic administration of the prepared SMD, the following toxicological changes were noted: a statistically very highly signifi cant (p = 50.001) decrease in the absolute weight of the male rat liver [26.55% decrease]; a statistically highly signifi cant (p50. 002) decrease in the relative percent weight of the male rat liver [19.45% decr.. View More»
  

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