Journal of Blood Disorders & Transfusion

Manar E Selim

Publications

• Research Article
  Electron and Scanning Microscopic Observations on the Syncytiotrophoblast Microvillous Membrane Contribution to Preeclampsia in Early Placental Rats
  Author(s): Manar E Selim, Nouf G Elshmry and El Hamidi A RashedManar E Selim, Nouf G Elshmry and El Hamidi A Rashed
  
  Pre-eclampsia is a pregnancy-specific syndrome characterized by new-onset hypertension and proteinuria, occurring usually after 20 weeks’ gestation. The current study was carried out on 60 female Wistar rats. Group I: included virgin non-pregnant rats. Group II: included pregnant rats that were received saline solution (0.5 ml/100 g body weight) subcutaneously daily starting from day 7 to day 14 of gestation and served as control group. Group III: included pregnant rats that were treated with bestatin dissolved in saline in a dose of (40.0 μg/ml)/100 g body weight subcutaneously and daily starting from the same day of gestation and for the same duration as mentioned for group II, to make an animal model of preeclampsia. Hence several possible mechanisms of the activation in pre-eclampsia can be considered, all dependent on the syncytiotrophoblast microvillous surface membrane.. View More»
  DOI: 10.4172/2155-9864.1000137

  Abstract PDF