Biology and Medicine

Makosha Patience Mamabolo

Publications

• Research Article
  Evaluation of Antigonorrhea Activity and Cytotoxicity of Helichrysum caespititium (DC) Harv. Whole Plant Extracts
  Author(s): Makosha Patience Mamabolo, Freddy Munyololo Muganza, Mutendela Tabize Olivier, Oyinlola Oluwunmi Olaokun and Lesiba Dick NemutavhananiMakosha Patience Mamabolo, Freddy Munyololo Muganza, Mutendela Tabize Olivier, Oyinlola Oluwunmi Olaokun and Lesiba Dick Nemutavhanani
  
  Over 80% of African population depends on traditional knowledge for their well-being, and especially on plants as medicines. Although Helichrysum caespititium is among plants that are commonly used by traditional healers in Africa, its biological activities are still not scientifi cally proven and reported. The primary objective of this study is to assess the antigonorrhea activity and cytotoxicity of H. caespititium whole plant. The plant material was subjected to a serial exhaustive extraction to obtain different solvent extracts using n-hexane, dichloromethane, methanol, and water. The antigonorrhea activity of the four plant extracts (n-hexane, dichloromethane, methanol, and water extracts) against 2008 WHO Neisseria gonorrhea reference strains and the toxicity of the extracts against rat liver cells were investigated. All four H. caespititium extracts showed good activity agai.. View More»
  DOI: 10.4172/0974-8369.1000422

  Abstract PDF