Journal of Clinical & Experimental Pharmacology

Machado RP

Publications

• Research Article
  Experimental Confirmation of the Utility of Nasturtium officinale Used Empirically as Mouth Lesion Repairing Promotor
  Author(s): Bettega PVC, Johann ACBR, Alanis LRA, Bazei IF, Miguel OG, Kocler CC, Lima AAS, Machado MAN, Machado RP, Rosa EAR, Yusuf S althobaiti, Atiah H Almalki, Abuhammad S and Gregio AMTBettega PVC, Johann ACBR, Alanis LRA, Bazei IF, Miguel OG, Kocler CC, Lima AAS, Machado MAN, Machado RP, Rosa EAR, Yusuf S althobaiti, Atiah H Almalki, Abuhammad S and Gregio AMT
  
  Nasturtium officinale R.Br. (Brassicaceae), ?watercress?, is an herbal plant widely consumed as food by many cultures. Along with this, it is used in folk medicine to help in treating asthma, bronchitis, hypertension, as well as other diseases. Rural Italian communities have used N. officinale as an adjuvant to cure bovine stomatitis without any scientific evidence that supports its use for such end. This study evaluated the efficacy of N. officinale as an adjuvant on the healing of traumatic ulcers on rat tongue dorsum. Method: In four control-experiment group-pairs (eight animals per group) there were punch induced 0.5 mm lesions on tongue dorsum, to mimic traumatic ulcers. Rats from control groups received saline solution onto lesions daily. Animals from experimental groups received oral solution containing 15% N. officinale ethanolic extract onto lesions. Animals were euthanized at 2.. View More»
  DOI: 10.4172/2161-1459.1000201

  Abstract PDF