Liaquat A
Dhaka
Bangladesh
Research Article
Nonalcoholic Fatty Liver Disease and its association with Insulin Resistance: A Study from Bangladeshi Newly Diagnosed Impaired Glucose Tolerance Subjects
Author(s): Israt AH and Liaquat AIsrat AH and Liaquat A
Background: Nonalcoholic fatty liver disease (NAFLD) is a clinicopathological condition strongly associated with obesity, type 2 diabetes, and metabolic syndrome. NAFLD is more prevalent in T2DM subjects but in the prediabetic state, particularly in impaired glucose tolerance (IGT) very, limited data are elucidated. The present study is aimed to examine the association of insulin resistance with NAFLD in subjects with newly diagnosed IGT. Methods: We studied 74 purposively recruited IGT [M/F, 34/40; age (ranges) in years, (25-64)] subjects whose NAFLD was confirmed by ultrasound assessment of the liver. IGT was diagnosed by 75 g OGTT as per WHO Group Study criteria. Serum glucose was measured by glucose-oxidase method. Serum insulin was measured by ELISA technique. Insulin resistance (HOMA-IR) was calculated by homeostasis model asses.. View More»
