Lamberto Re
University of Ancona and Medinat Clinic,
Via Fazioli 22, 60021 Camerano
Italy
Review Article
Molecular Aspects and New Biochemical Pathways Underlying Ozone Effects
Author(s): Lamberto ReLamberto Re
In recent years, emphasis and attention have been focused on the use of medical ozone (O3). Despite its huge diffusion, certain confusion still persists concerning its potential toxicity as a strong oxidant. Although its use as safety remedy in the medical field has been described since the last century, this confusion still represents a major factor preventing its full acceptance. Furthermore, the use of ozone therapy (OT) in specialities so different like neurology, orthopaedics, internal medicine, sports medicine, dermatology, endocrinology and others makes difficult the collocation of OT as a single specialist branch. In this context, the apparent heterogeneous network of diseases in which OT seems to be active resembles those proposed for the nuclear factor (erythroid-derived 2)-like 2 (NRF2) pathway. This fact, extremely exciting by a pure pharmacological point of view, may caus.. View More»
DOI:
10.4172/2161-1459.1000248