Katsunobu Sakurai
Japan
Research Article
Evaluation of the Prognostic Significance of "High-risk Stigmata" in the International Consensus Guidelines 2012 for Intraductal Papillary Mucinous Neoplasm
Author(s): Kenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Kotaro Miura, Kohei Nishio, Katsunobu Sakurai, Takahiro Toyokawa, Bunzo Nakata, Akihiro Murata, Sadatoshi Shimizu, Sayaka Tanaka, Masahiko Ohsawa, Masaichi Ohira and Kosei HirakawaKenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Kotaro Miura, Kohei Nishio, Katsunobu Sakurai, Takahiro Toyokawa, Bunzo Nakata, Akihiro Murata, Sadatoshi Shimizu, Sayaka Tanaka, Masahiko Ohsawa, Masaichi Ohira and Kosei Hirakawa
Study Background: In the International Consensus Guidelines 2012 for intraductal papillary mucinous neoplasm (IPMN), ‘high-risk stigmata’ (HRS) were described as indications for resection. The purpose of this study was to evaluate the prognostic meaning of HRS in the 2012 guidelines.
Method: Clinical and pathological data from 98 patients who underwent pancreatic resection for IPMN at our institution between 1994 and 2014 were retrospectively analyzed.
Results: The 98 resected IPMNs were categorized as demonstrating no criteria (NC) (n=18), worrisome features (WF) (n=39), or HRS (n=46) according to the guidelines. By multivariate analysis, positive lymph node metastasis and HRS were significantly identified as independent.. View More»
