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Juana Maria Jiménez-Vargas
Juana Maria Jiménez-Vargas
Mexico
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Mini Review
Scorpine-Like Peptides
Author(s): Karen Luna-RamÃrez, Juana Maria Jiménez-Vargas and Lourival D PossaniKaren Luna-Ramírez, Juana Maria Jiménez-Vargas and Lourival D Possani
Scorpine-like peptides are intriguing and unique compounds of scorpion venom. They possess two well-defined regions that confers them bi-functionality. The N-terminal region is similar to scorpion antimicrobial peptides lacking disulfide bridges, whereas the C-terminal region contains six cysteines forming three disulfide bridges that tightly bind the peptide. Scorpine-like peptides have shown activity against bacteria (i.e. B. subtilis, K. pneumoniae, P. aeruginosa), fungi and also as potassium channel blockers. Additionally, they have been successful in controlling malaria and some types of viruses. .. View More»
DOI: 10.4172/2168-9431.1000138