Biology and Medicine

Juan Carlos Souto

Publications

• Research Article
  The Relationship between Leukocyte Counts and Venous Thromboembolism: Results from RETROVE Study
  Author(s): Noelia Vilalta, Miquel Vázquez-Santiago, Biel Cuevas, Raquel Macho, Angel Remacha, Marina Carrasco, José Mateo, Juan Millón, José Manuel Soria and Juan Carlos SoutoNoelia Vilalta, Miquel Vázquez-Santiago, Biel Cuevas, Raquel Macho, Angel Remacha, Marina Carrasco, José Mateo, Juan Millón, José Manuel Soria and Juan Carlos Souto
  
  Introduction: Different studies have shown a possible increased risk of venous thromboembolism (VTE) and arterial thrombosis in patients with an increased leukocyte count. The underlying mechanisms are not completely understood, but they could partly be explained by the role that white blood cells play in inflammation. Our objective is to investigate investigated the relationship between leukocyte counts and VTE. Material and methods: Analyses were performed in 400 patients and 400 control subjects of the RETROVE (Riesgo de Enfermedad TROmboembólica VEnosa) Study. To evaluate the odds ratio (OR) for VTE of leukocyte counts we used an unconditional logistic regression analysis taking into account the confounders. Results: We observed more spontaneous (273, 68.3%) than non–spontaneous (127, 31.8%) VTE. Monocyte counts showed a strong association with thrombosis risk: For th.. View More»
  DOI: 10.4172/0974-8369.1000400

  Abstract PDF