JP. Deslypere
Singapore
Research Article
Assessment of Sudomotor Function to Predict Future Abnormalities of Glucose Tolerance in at Risk Population
Author(s): A. Ramachandran, A. Moses, C. Snehalatha, A. S. Shetty, A. Catherin Seeli, S. Singvi, JP. Deslypere, P. Brunswick and JH. CalvetA. Ramachandran, A. Moses, C. Snehalatha, A. S. Shetty, A. Catherin Seeli, S. Singvi, JP. Deslypere, P. Brunswick and JH. Calvet
Aims: This study done in subjects with an initial normal glucose tolerance (NGT) was to assess the ability of EZSCAN, a new device developed to evaluate sudomotor function, to predict future abnormalities in glucose tolerance.
Methods: South Asian (Indian) subjects (n= 69, 48% male, mean age 42 ± 9 years, mean BMI 28 ± 5 kg/m 2 ) diagnosed as NGT with a previous oral glucose tolerance test (OGTT, T0) underwent a frequently sampled OGTT (FSOGTT), 8 months later (T8). At both times EZSCAN tests were done. Using the AUC glucose and AUC insulin measured by the FSOGTT, subjects were categorised as normal, high AUC insulin or isolated high AUC glucose . Odds ratio (OR) for having high AUC insulin or isolated high AUC glucose vs normal was computed by logistic regression .. View More»
