Advances in Pharmacoepidemiology and Drug Safety

Jolliet P

Publications

• Research Article
  Selective Serotonin Reuptake Inhibitors, are They All Equal? A Pharmacoepidemiological Study
  Author(s): Péron E, Hardouin JB, Sébille V, Feuillet F, Wainstein L, Chaslerie A, Pivette J, Jolliet P and Victorri-Vigneau CPéron E, Hardouin JB, Sébille V, Feuillet F, Wainstein L, Chaslerie A, Pivette J, Jolliet P and Victorri-Vigneau C
  
  Introduction: According to the French health authorities’ guidelines relative to depression and anxiety disorder treatments, six Selective Serotonin Reuptake Inhibitors are available for prescription as a first-line of treatment. The guidelines suggest equivalence between these treatment options, but studies diverge regarding efficacy and safety profiles. Moreover, conditions in clinical trials are strictly controlled and do not truly reflect real life utilization. The objective of this study was to evaluate differences in efficacy and/or safety between these six selective serotonin reuptake inhibitors in real conditions of use. Methods: Efficacy and safety were evaluated using a regional database of the French national health insurance. Patients who received a selective serotonin reuptake inhibitor for a new depressive disorder and who were compliant to the treatment for a peri.. View More»
  DOI: 10.4172/2167-1052.1000203

  Abstract PDF